Nate's Locker is a locker owned by Nate Wright on the second floor. Nate mentioned that it was number 217 in a comic, and 666 in another. Nate's dad claims that Nate cannot remember the combo of the locker, which is probably untrue since he includes them in his comics as he has every means of access to it.
The locker is known to be very messy, although Nate claims that he has a filing system. When it is open, the contents of the locker spill out. According to Gina, people could get knocked over. The first strip had the sound "SSHWSSH!", which evolved. The sound evolved into "SHOOSH!", "SSSHK!", "KSSSSH!", "KSSSCH!", and finally "FOOOOM!"
A bunch of random items is inside the locker, including:
Nate installed a vacuum inside his locker to clean up the mess after opening it. It can be activated by pressing a button beside it. However, this vacuum is too powerful and it can trap his friends inside.