Big Nate's Greatest Hits is a comic strip collection in the Big Nate series. The book featured Nate going out with Angie, though their break-up was not part of the book. It contained parts of Big Nate: Pray For A Fire Drill, Big Nate: Makes a splash, and Big Nate: Dibs on this chair.
- Nate goes to Summer School.
- It features Ellen Wright working at Dilly Burger.
- First appearance of Angie.
- Nate and Angie meet in summer school.
- Nate and Angie start dating.
- Big Nate's Greatest Hits is a compilation of Big Nate: Dibs On This Chair, Big Nate: Makes a Splash, and Big Nate: Pray for a Fire Drill.
- It contains all of the strips from 1997.