A Thanksgiving Prayer was a poem written by Nate Wright. He wrote it on Thanksgiving, shortly after he got his surgical cast removed. After the poem, on the fourth panel, Lincoln Peirce wished a happy thanksgiving to everyone from Big Nate himself.
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I thank you, Lord, for all the things that make my life so descent. I thank you for the blessings in my past (and those more recent). I thank you for my dear old Dad. (I hope that you will note that.) I even thank you for my sis. (I can't believe I wrote that.) But most of all I'm thankful that I got my stupid cast off. And now that I can draw again, my art career will blast off!"